CS Cancer Solutions - Structured Oncology Intelligence
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Israel Cancer Research

#1 Per Capita in Cancer Innovation & Immunotherapy Leadership

#1

Per Capita Innovation

Globally in cancer research

99%+

Liquid Biopsy Accuracy

Early cancer detection

80%

Side Effect Reduction

Nanoparticle delivery

Major Research Breakthroughs

World-Leading Cancer Immunotherapy Innovation

Ongoing

Israel ranks #1 globally per capita in cancer immunotherapy research, developing breakthrough checkpoint inhibitors, CAR-T enhancements, and cancer vaccines.

Weizmann Institute of Science, multiple biotech companies

Impact:

Pioneering next-generation immunotherapy worldwide

AI-Powered Cancer Drug Discovery

2022-2024

Israeli AI companies use machine learning to design novel cancer drugs in months instead of years, identifying compounds missed by traditional methods.

Israeli tech sector, Sheba Medical Center

Impact:

Revolutionizing pharmaceutical development speed

Precision Oncology & Liquid Biopsy Leadership

2023-2024

Israel developed advanced liquid biopsy technologies detecting cancer DNA in blood with 99%+ accuracy, enabling ultra-early diagnosis.

Weizmann Institute, Sheba Medical Center

Impact:

Catching cancer before it becomes visible on scans

Cancer Vaccine Breakthroughs

2022-2024

Israeli researchers developed personalized cancer vaccines that train the immune system to attack patient-specific tumor mutations.

Hadassah Medical Center, Tel Aviv University

Impact:

Custom vaccines for each patient's unique cancer

Medical Cannabis Cancer Research

Ongoing

Israel leads global research on medical cannabis for cancer pain management and potential anti-tumor effects, with world's largest clinical database.

Multiple Israeli hospitals and research centers

Impact:

Evidence-based cannabis oncology protocols

Nanotechnology Cancer Therapy

2022-2024

Israeli scientists pioneered nanoparticle drug delivery systems that target cancer cells while sparing healthy tissue, reducing side effects by 80%.

Technion - Israel Institute of Technology

Impact:

Safer, more effective chemotherapy delivery

Prostate Cancer Focal Therapy Innovation

2021-2024

Israel developed targeted ablation techniques for prostate cancer preserving sexual and urinary function in 95%+ of patients.

Sheba Medical Center

Impact:

Treating prostate cancer without major side effects

Cancer Big Data & Genomics Integration

2020-2024

Israel's national cancer database integrates genomic, clinical, and outcome data for 100% of cancer patients, enabling AI-driven treatment optimization.

Israeli Ministry of Health, National Cancer Registry

Impact:

Population-wide precision oncology

Leading Research Institutions

Weizmann Institute of Science

Rehovot

World-renowned research institute. Leading cancer immunology, liquid biopsy, and molecular biology research. Ranks top 10 globally in cancer research impact.

Key Specialties:

Immunotherapy
Liquid Biopsy
Cancer Biology
Drug Discovery

Sheba Medical Center

Tel Aviv

Middle East's largest hospital. Pioneer in AI diagnostics, precision oncology, and minimally invasive cancer treatments. International medical tourism hub.

Key Specialties:

AI Diagnostics
Precision Oncology
Prostate Cancer
Medical Tourism

Hadassah Medical Center

Jerusalem

Leading academic medical center. Breakthrough research in cancer vaccines, immunotherapy, and pediatric oncology.

Key Specialties:

Cancer Vaccines
Immunotherapy
Pediatric Oncology

Tel Aviv University & Medical Center

Tel Aviv

Major research university and hospital. Nanotechnology, cancer genetics, and translational research.

Key Specialties:

Nanotechnology
Cancer Genetics
Translational Research
Active Clinical Trials in Israel

Israel welcomes international patients to cutting-edge clinical trials

Personalized Cancer Vaccine (mRNA-based)

Phase 2

Custom mRNA vaccines targeting each patient's unique tumor mutations for melanoma, lung, and colorectal cancers.

Sheba Medical Center, Hadassah
Active recruitment

AI-Designed CAR-T for Solid Tumors

Phase 1/2

Artificial intelligence-optimized CAR-T cells engineered to penetrate and destroy solid tumors (pancreatic, ovarian, lung).

Weizmann Institute, Sheba Medical Center
Active recruitment

Nanoparticle Chemotherapy Delivery

Phase 2

Targeted nanoparticles delivering chemotherapy directly to tumor cells, reducing systemic side effects by 80%+.

Technion, Tel Aviv Medical Center
Active recruitment

Liquid Biopsy Early Detection Program

Population Study

Nationwide screening using blood tests to detect multiple cancers years before symptoms appear.

Israeli Ministry of Health, multiple hospitals
Ongoing enrollment

Want to learn about more Israeli clinical trials? Search our database or contact our team.

Clinical Trials in Israel

Registry-listed trials for Israel currently tracked in our database, sourced from public trial registries.

Efficacy and Safety of Astragalus for Symptomatic Alleviation in Patients With High-grade Lymphoma Treated With Chemotherapy: a Double-blind Randomized Placebo-controlled Trial

Phase III
Not yet recruiting
NCT06510530
View registry record

Efficacy and Safety of Astragalus for Symptomatic Alleviation in Patients With High-grade Lymphoma Treated With Chemotherapy: a Double-blind Randomized Placebo-controlled Trial

Phase III
Not yet recruiting
NCT06510530
View registry record

Efficacy and Safety of Astragalus for Symptomatic Alleviation in Patients With High-grade Lymphoma Treated With Chemotherapy: a Double-blind Randomized Placebo-controlled Trial

Phase III
Not yet recruiting
NCT06510530
View registry record

A Phase 2, Open-label, Multicenter Study to Determine the Safety, Tolerability, and Efficacy of MK-1045 in Participants With Hematologic Malignancies

Phase II
Not yet recruiting
NCT07709000
View registry record

A Phase 2, Open-label, Multicenter Study to Determine the Safety, Tolerability, and Efficacy of MK-1045 in Participants With Hematologic Malignancies

Phase II
Not yet recruiting
NCT07709000
View registry record

A Phase 2/3, Randomized, Open-label, Active-comparator-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Bomedemstat (MK-3543) Versus Best Available Therapy in Participants With Polycythemia Vera Who Have an Inadequate Response to or Are Intolerant to Hydroxyurea

Phase II
Recruiting
NCT07722611
Polycythemia Vera
View registry record

A Phase 2/3, Randomized, Open-label, Active-comparator-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Bomedemstat (MK-3543) Versus Best Available Therapy in Participants With Polycythemia Vera Who Have an Inadequate Response to or Are Intolerant to Hydroxyurea

Phase II
Recruiting
NCT07722611
View registry record

A Phase 2/3, Randomized, Open-label, Active-comparator-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Bomedemstat (MK-3543) Versus Best Available Therapy in Participants With Polycythemia Vera Who Have an Inadequate Response to or Are Intolerant to Hydroxyurea

Phase II
Recruiting
NCT07722611
View registry record

A Phase 2/3, Randomized, Open-label, Active-comparator-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Bomedemstat (MK-3543) Versus Best Available Therapy in Participants With Polycythemia Vera Who Have an Inadequate Response to or Are Intolerant to Hydroxyurea

Phase II
Recruiting
NCT07722611
View registry record

A Phase 3, Open-Label, Multicenter, Randomized Study of Raludotatug Deruxtecan (MK-5909, R-DXd) With or Without Bevacizumab Versus Standard-of-Care Platinum-Based Doublet Chemotherapy With or Without Bevacizumab in Participants With Advanced Platinum-Sensitive High-Grade Serous or High-Grade Endometrioid Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Have Progressed During First-Line PARPi Maintenance (ENGOT-ov107 / GOG-3142 / REJOICE-Ovarian05)

Phase III
Not yet recruiting
NCT07743164
View registry record

A Phase 3, Open-Label, Multicenter, Randomized Study of Raludotatug Deruxtecan (MK-5909, R-DXd) With or Without Bevacizumab Versus Standard-of-Care Platinum-Based Doublet Chemotherapy With or Without Bevacizumab in Participants With Advanced Platinum-Sensitive High-Grade Serous or High-Grade Endometrioid Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Have Progressed During First-Line PARPi Maintenance (ENGOT-ov107 / GOG-3142 / REJOICE-Ovarian05)

Phase III
Not yet recruiting
NCT07743164
View registry record

A Phase 3, Open-Label, Multicenter, Randomized Study of Raludotatug Deruxtecan (MK-5909, R-DXd) With or Without Bevacizumab Versus Standard-of-Care Platinum-Based Doublet Chemotherapy With or Without Bevacizumab in Participants With Advanced Platinum-Sensitive High-Grade Serous or High-Grade Endometrioid Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Have Progressed During First-Line PARPi Maintenance (ENGOT-ov107 / GOG-3142 / REJOICE-Ovarian05)

Phase III
Not yet recruiting
NCT07743164
View registry record

Latest Research Ecosystem Developments

Israel — Israel's oncology research ecosystem is experiencing robust growth, marked by significant philanthropic investment, the launch of world-first clinical trials for novel RNA therapies, and the expansion of specialized cancer care facilities.

Updated October 9, 2026

World-First Clinical Trial for RNA-Based Pancreatic Cancer Treatment

Tel Aviv Sourasky Medical Center has initiated the first global clinical trial for SIL204, an experimental RNA-based therapy developed by Silexion Therapeutics to target KRAS mutations in pancreatic cancer.

The Jerusalem Post

ICRF Surpasses $100 Million in Lifetime Funding

The Israel Cancer Research Fund (ICRF) reached a major milestone in 2025, surpassing $100 million in total lifetime funding for cancer research while celebrating its 50th anniversary.

Israel Cancer Research Fund

Multi-Million Dollar Grant Cycle for 2026-2027

The ICRF announced $5.35 million in new research grants for the 2026-2027 cycle, supporting 38 innovative projects spanning artificial intelligence, liquid biopsy, and immunotherapy.

Israel Cancer Research Fund

Expansion of Oncology-Hematology Facilities

Hillel Yaffe Medical Center inaugurated a new, advanced Oncology-Hematology Center in September 2025, supported by a significant donation from the Israel Cancer Association.

Hillel Yaffe Medical Center

Strategic Investment in Diverse Cancer Research

Recent funding cycles have prioritized a wide range of critical research areas, including CAR-T cell therapy optimization, pediatric oncology, and the role of the microbiome in immunotherapy response.

Israel Cancer Research Fund

This section is refreshed on a recurring schedule. Entries are AI-assisted research signals organized from public oncology sources and should be verified against the original sources. Information is educational and does not constitute medical advice.

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