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Belgium Cancer Research

European Clinical Trials Hub & Universal CAR-T Pioneer

1,500+

EORTC Clinical Trials

35 countries

85%+

Pediatric Survival Rate

World-class outcomes

100%

Genomic Profiling Access

All cancer patients

Major Research Breakthroughs

European Clinical Trials Headquarters (EORTC)

1962-Present

European Organization for Research and Treatment of Cancer (EORTC) headquartered in Brussels coordinates 1,500+ cancer clinical trials across 35 countries, world's largest multinational trials network.

EORTC

Impact:

Coordinating Europe's cancer research ecosystem

CAR-T Therapy Innovation Hub

2022-2024

Belgium's Ghent University and KU Leuven pioneered universal CAR-T cells (off-the-shelf) eliminating 3-week manufacturing wait, making therapy available immediately for emergency cases.

Ghent University, KU Leuven

Impact:

Instant CAR-T therapy availability

Proton Therapy Center of Excellence

2019-Present

Belgium operates Europe's most advanced proton therapy center (IBA Proteus ONE) treating 1,000+ patients annually with pencil-beam scanning precision unavailable elsewhere.

UZ Leuven, IBA

Impact:

Ultra-precise radiation therapy

Cancer Immunotherapy Leadership

2010-2020

Belgian researchers at VIB-UGent discovered key immune checkpoint mechanisms, contributing to development of 5+ FDA-approved immunotherapy drugs including nivolumab pathways.

VIB, Ghent University

Impact:

Foundation of modern immunotherapy

Liquid Biopsy Technology Pioneer

2021-2024

Belgium's Genomic Vision and multiple academic centers developed blood tests detecting cancer mutations with 98%+ accuracy, approved for clinical use across EU.

VIB, KU Leuven

Impact:

Non-invasive cancer diagnosis and monitoring

Pediatric Cancer Research Excellence

Ongoing

Belgium achieves 85%+ childhood cancer survival rates through national pediatric oncology network coordinating treatment across all hospitals, among world's best outcomes.

Belgian Children's Cancer Registry

Impact:

Saving children's lives with world-class care

Precision Medicine Integration

2020-Present

Belgium implemented nationwide genomic profiling for all cancer patients through public healthcare, providing personalized treatment recommendations to 100% of patients.

Belgian healthcare system

Impact:

Universal precision oncology

Universal Healthcare Cancer Success

Ongoing

Belgium's healthcare system achieves 65%+ 5-year cancer survival with equitable access for all citizens, proving comprehensive coverage delivers excellent results.

Belgian healthcare system

Impact:

Model for accessible cancer care

Leading Research Institutions

European Organization for Research and Treatment of Cancer (EORTC)

Brussels

World's largest multinational cancer trials organization. Coordinates 1,500+ trials across 35 countries, setting standards for cancer research globally.

Key Specialties:

Clinical Trials
International Coordination
Research Standards

KU Leuven Cancer Institute

Leuven

Belgium's premier cancer research center. Leading CAR-T innovation, proton therapy, and precision oncology. 1,000+ researchers.

Key Specialties:

CAR-T Therapy
Proton Therapy
Precision Medicine

VIB (Flanders Institute for Biotechnology)

Ghent, Brussels

World-class life sciences research institute. Breakthrough discoveries in cancer immunology, genomics, and drug development.

Key Specialties:

Cancer Immunology
Genomics
Drug Discovery

Institut Jules Bordet

Brussels

Leading comprehensive cancer center. Excellence in breast cancer research, immunotherapy, and clinical trials. 8,000+ patients annually.

Key Specialties:

Breast Cancer
Immunotherapy
Clinical Excellence
Active Clinical Trials in Belgium

Belgium welcomes international patients to cutting-edge clinical trials

Universal Off-the-Shelf CAR-T

Phase 1/2

Ready-to-use CAR-T cells requiring no patient-specific manufacturing, available immediately for emergency blood cancer cases.

Ghent University, KU Leuven
Active recruitment

Precision Proton Beam Therapy

Treatment Program

Ultra-precise pencil-beam proton therapy for brain, spine, and pediatric cancers minimizing radiation to healthy tissue.

UZ Leuven
Accepting patients

Liquid Biopsy Monitoring Program

Phase 3

Blood test monitoring for cancer recurrence and treatment response across multiple cancer types with 98%+ accuracy.

VIB, KU Leuven
Active recruitment

EORTC Multi-National Immunotherapy Trials

Phase 2/3

Pan-European trials testing novel immunotherapy combinations for melanoma, lung, and kidney cancers across 35 countries.

EORTC, multiple European centers
Active recruitment

Want to learn about more Belgian clinical trials? Search our database or contact our team.

Clinical Trials in Belgium

Registry-listed trials for Belgium currently tracked in our database, sourced from public trial registries.

Epcoritamab Plus Venetoclax Plus Ibrutinib in Patients With Chronic Lymphocytic Leukemia With TP53 Alterations

Phase II
Not yet recruiting
NCT07738887
View registry record

A Phase 1/2a, First-in-human, Open-label, Dose-escalating Study With a Safety Expansion Cohort to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-tumour Activity of TAX2 in Patients With Relapsed/Refractory Advanced/Metastatic Solid Tumours

Phase I
Not yet recruiting
NCT07688148
Solid Tumor Cancers
View registry record

A Phase Ib/II, Open-label, Safety and Tolerability Trial of Intravenous Obrixtamig in Combination With Pumitamig and Standard of Care (Carboplatin, Etoposide) in Patients With Extensive-stage Small Cell Lung Carcinoma

Phase I
Not yet recruiting
NCT07843940
Extensive-stage Small Cell Lung Carcinoma
Advanced Small Cell Lung Cancer
View registry record

SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates

Phase II
Not yet recruiting
NCT07474558
View registry record

SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates

Phase II
Not yet recruiting
NCT07474558
View registry record

SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates

Phase II
Not yet recruiting
NCT07474558
View registry record

SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates

Phase II
Not yet recruiting
NCT07474558
View registry record

SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates

Phase II
Not yet recruiting
NCT07474558
View registry record

A Phase 2 Open-Label, Multi-Center Study of BMS-986504 as Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion

Phase II
Recruiting
NCT07492680
Solid Tumors
View registry record

Randomized Phase II Selection Trial of FLASH Versus Conventional Radiotherapy for Participants With Localized Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

Phase II
Not yet recruiting
NCT07455331
Cutaneous Squamous Cell Carcinoma (CSCC)
Basal Cell Carcinoma (BCC)
View registry record

Randomized Phase II Selection Trial of FLASH Versus Conventional Radiotherapy for Participants With Localized Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

Phase II
Not yet recruiting
NCT07455331
View registry record

Randomized Phase II Selection Trial of FLASH Versus Conventional Radiotherapy for Participants With Localized Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

Phase II
Not yet recruiting
NCT07455331
View registry record

Latest Research Ecosystem Developments

Belgium — Belgium's oncology ecosystem is experiencing significant growth in 2025-2026, characterized by expanded clinical trial infrastructure, strategic international biopharmaceutical partnerships, and innovative diagnostic breakthroughs.

Updated October 16, 2026

Inauguration of the Novel Treatment Unit at Jules Bordet Institute

In November 2025, the Jules Bordet Institute opened a dedicated clinical trial unit featuring biosafety level 2 certification, enabling the facility to conduct advanced research on viral agents and innovative cell therapies.

BioWin

Strategic Alliance Between UCB and Cancer Research UK

In May 2026, Belgian biopharmaceutical company UCB announced a multi-project alliance with Cancer Research UK and Cancer Research Horizons to accelerate the discovery and preclinical development of novel oncology therapeutics.

UCB

Record Funding Raised by Télévie 2026

The 2026 edition of the Télévie campaign raised over 13.4 million euros, providing essential financial support for fundamental cancer research and the development of new treatment modalities in Belgium.

FNRS

Development of Revolutionary Multi-Marker Cancer Screening Test

Researchers at UZ Leuven and KU Leuven developed a blood test that detects both genetic and epigenetic alterations, with commercialization efforts led by the Belgian biotech firm OncoDNA targeting clinical implementation by late 2026.

Focus on Belgium

Expansion of Clinical Trial Activity in 2026

As of October 2026, Belgium recorded 398 new clinical trials with local involvement, reflecting a robust landscape of both domestic and international collaborative research across major oncology centers.

AcademicLabs

This section is refreshed on a recurring schedule. Entries are AI-assisted research signals organized from public oncology sources and should be verified against the original sources. Information is educational and does not constitute medical advice.

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